Transcriptomic analysis provides new insights into the secondary follicle growth in spotted scat (Scatophagus argus)

Spotted scat ( Scatophagus argus ) is an important mariculture fish that of great economic significance in East and Southeast Asia. To date, there are no studies on ovary development regulation S. . Herein, the transcriptome profiles at different stages were constructed, genes pathways potentially involved secondary follicle growth identified. A total 25,426 detected by sequencing mRNAs from libraries stage III (n=3) IV (n=3). Notably, 2950 716 up-regulated down-regulated ovary, respectively, compared to ovary. The differentially expressed (DEGs) found be mostly regulating steroidogenesis, vitellogenesis, lipid metabolism, meiosis. Up-regulation steroid hormone synthesis pathway fshr , cyp17a1 foxl2 insulin-like factor igf1r ifg2r igfbp1 igfbp3 igfbp7 was possibly reason for increased serum estrogen. Moreover, ppara ppard fabp3 lpl droplet formation oocyte. Many DEGs cellular cycle, meiosis, cAMP or cGMP hydrolysis, indicating meiosis restarted In addition, numerous TGF-beta signal This transcript dataset forms a baseline investigating functional associated with oogenesis